Chapter+14+&+15+Mendelian+Genetics

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1. Explain how Mendel’s particulate mechanism differed from the blending theory of inheritance.
 * CHAPTER 14 **
 * MENDEL AND THE GENE IDEA **
 * Gregor Mendel’s Discoveries **

2. Define the following terms: true breeding, hybridization, monohybrid cross, P generation, F 1 generation, F 2 generation.

3. List and explain the four components of Mendel’s hypothesis that led him to deduce the law of segregation.

<span style="font-family: 'Garamond','serif'; font-size: 16px;">4. Explain how a testcross can be used to determine if an individual with the dominant phenotype is homozygous or heterozygous.

<span style="font-family: 'Garamond','serif'; font-size: 16px;">5. State Mendel’s law of independent assortment and describe how this law can be explained by the behavior of chromosomes during meiosis.

<span style="font-family: 'Garamond','serif'; font-size: 16px;">6. Explain why it was important that Mendel used large sample sizes in his studies.

<span style="font-family: 'Garamond','serif'; font-size: 16px;">7. Give an example of incomplete dominance and explain why it does not support the blending theory of inheritance.
 * <span style="font-family: 'Garamond-Bold','sans-serif'; font-size: 16px;">Extending Mendelian Genetics **

<span style="font-family: 'Garamond','serif'; font-size: 16px;">8. Explain why dominant alleles are not necessarily more common in a population. Illustrate your explanation with an example.

<span style="font-family: 'Garamond','serif'; font-size: 16px;">9. Describe the inheritance of the ABO blood system and explain why the I <span style="font-family: 'Garamond','serif'; font-size: 9px;">A <span style="font-family: 'Garamond','serif'; font-size: 16px;">and I <span style="font-family: 'Garamond','serif'; font-size: 9px;">B <span style="font-family: 'Garamond','serif'; font-size: 16px;">alleles are said to be <span style="font-family: 'Garamond','serif';">co-dominant.

<span style="font-family: 'Garamond','serif'; font-size: 16px;">10. Define and give examples of pleiotropy and epistasis.

<span style="font-family: 'Garamond','serif'; font-size: 16px;">11. Explain how carrier recognition, fetal testing, and newborn screening can be used in genetic screening and counseling.
 * <span style="font-family: 'Garamond-Bold','sans-serif'; font-size: 16px;">Mendelian Inheritance in Humans **

<span style="font-family: 'Garamond','serif'; font-size: 16px;">12. Describe the chromosome theory of inheritance.
 * <span style="font-family: 'Garamond-Bold','sans-serif'; font-size: 16px;">CHAPTER 15 **
 * <span style="font-family: 'Garamond-Bold','sans-serif'; font-size: 16px;">THE CHROMOSOMAL BASIS OF INHERITANCE **
 * <span style="font-family: 'Garamond-Bold','sans-serif'; font-size: 16px;">Learning objectives: **
 * <span style="font-family: 'Garamond-Bold','sans-serif'; font-size: 16px;">Relating Mendelian Inheritance to the Behavior of Chromosomes **

<span style="font-family: 'Garamond','serif'; font-size: 16px;">13. Describe how sex is genetically determined in humans and explain the significance of the //<span style="font-family: 'Garamond-Italic','sans-serif'; font-size: 16px;">SRY //<span style="font-family: 'Garamond','serif'; font-size: 16px;">gene.
 * <span style="font-family: 'Garamond-Bold','sans-serif'; font-size: 16px;">Sex Chromosomes **

<span style="font-family: 'Garamond','serif'; font-size: 16px;">14. Explain why sex-linked diseases are more common in human males.

<span style="font-family: 'Garamond','serif'; font-size: 16px;">15. Distinguish between unlinked genes, linked genes and sex-linked genes.
 * <span style="font-family: 'Garamond-Bold','sans-serif'; font-size: 16px;">Linked Genes **

<span style="font-family: 'Garamond','serif'; font-size: 16px;">16. Explain how nondisjunction can lead to aneuploidy.
 * <span style="font-family: 'Garamond-Bold','sans-serif'; font-size: 16px;">Errors and Exceptions in Chromosomal Inheritance **

<span style="font-family: 'Garamond','serif'; font-size: 16px;">17. Define polyploidy. Explain how these major chromosomal changes occur and describe possible consequences.

<span style="font-family: 'Garamond','serif'; font-size: 16px;">18. Distinguish among deletions, duplications, inversions, and translocations.

<span style="font-family: 'Garamond','serif'; font-size: 16px;">19. Describe the type of chromosomal alterations responsible for the following human disorders: Down syndrome, Klinefelter syndrome, Turner syndrome, //<span style="font-family: 'Garamond-Italic','sans-serif'; font-size: 16px;">cri du chat //<span style="font-family: 'Garamond','serif'; font-size: 16px;"> syndrome, and chronic myelogenous leukemia.